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Now showing items 658-677 of 2671
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E-pharmacophore based virtual screening for identification of dual specific PDE5A and PDE3A inhibitors as potential leads against cardiovascular diseases
(Informa UK Limited, 17.04.2020)The need of circumventing life-threatening cardiovascular disorders (CVDs) and pulmonary hypertension (PHT) worldwide prompts researchers to develop effective therapeutic agents. Crucial role of cyclic nucleotide ... -
E-pharmacophore mapping combined with virtual screening and molecular docking to identify potent and selective inhibitors of P90 Ribosomal S6 Kinase (RSK)
(Turkish Pharmacists Association, 2016)The P90 ribosomal S6 kinases (RSK) are a family of serine/threonine protein kinases and are shown to be involved in cancer cell proliferation. The lack of highly selective inhibitors and also the lack of structural information ... -
Early - adulthood caloric restriction is beneficial to improve renal redox status as future anti - aging strategy in rats
(Elsevier B.V., 10.2020)Aims: Caloric restriction (CR) is an experimental approach proposed to alleviate age-related oxidative damage. In the present study, we investigated the consequences of CR on renal redox homeostasis in rats at a specific ... -
Early outcomes of fenestrated intra‐extracardiac Fontan procedure: Insights, experiences, and expectations
(Wiley-Blackwell, 2022)Abstract Background: Intraextracardiac Fontan procedure (FP) aimed to combine the advantages of lateral tunnel and extracardiac conduit modifications of the original technique. Herein, we present our early outcomes in ... -
Early results of ring-reinforced conduit and curved porcine patch in Sano-Norwood procedure
(WILEY, 2019)Background Patch augmentation of the aortic arch as well as construction of an unobstructed pulmonary blood supply are two important surgical targets in patients with hypoplastic left heart syndrome. In this report, we ... -
Ebelikte holistik yaklaşım
(Biruni Üniversitesi, 2021)Tıbbi bilimlerin amacı, hastalıkları iyileştirme esasına dayandığından dolayı gebelik ve doğumda yapılan bütün tıbbi müdahaleler, bu hastalığı iyileştirme esasına dayanır. Oysa ki geleneksel ebelik felsefesine göre gebelik ... -
Ebeveyn algısıyla çocuklardaki iştahsızlık durumu arasındaki ilişkinin belirlenmesi
(Biruni Üniversitesi Sağlık Bilimleri Enstitüsü, 2019)Bu çalışma, okul öncesi dönem çocuklarının annelerinden alından veriler doğrultusunda, çocuklardaki iştahsızlık ve ebeveyn tutumları arasındaki ilişkinin değerlendirilmesini amaçlamaktadır. Araştırma için yaşları 2 ile 6 ... -
Ebeveynlerin çocuk diş macunu seçimini etkileyen faktörlerin değerlendirilmesi
(Ege Üniversitesi, 2020)Amaç: Türkiye’de piyasada farklı özelliklerde çok sayıda diş macunu bulunmaktadır. Bu çalışmanın amacı ebeveynlerin çocukları için diş macunu seçimini etkileyen faktörlerin değerlendirilmesidir. Gereç ve Yöntem: Ağustos ... -
Ebeveynlerin öz yeterlik algılarıyla duygu sosyalleştirme davranışları arasındaki ilişkinin incelenmesi
(Biruni Üniversitesi, 2020)Bu çalışmada ebeveynlerin öz yeterlik algıları ile duygu sosyalleştirme davranışları arasındaki ilişki incelenmiştir. Araştırmanın örneklemini Türkiye’de ikamet eden 2-6 yaş arası çocuğu olan 150 ebeveyn (%72 Kadın, %28 ... -
Edirne’nin içme suyu fluor oranı farklı 3 ilçesinde dental fluorozis ve diş çürüğü prevalansının değerlendirilmesi
(Yeditepe Üniversitesi Diş Hekimliği Fakültesi, 08.03.2019)Amaç: Çalışmamızda Edirne’nin 3 ilçesinde içme sularındaki fluor seviyeleri belirlenerek bölgede yaşayan çocuklarda dental fluorozis ve diş çürüğü görülme sıklığı değerlendirilmiştir. Gereç ve Yöntem: Edirne ilinde, Kuzey ... -
The efect of diferent irrigation and disinfection methods on post-operative pain in mandibular molars: A randomised clinical trial
(BMC, 2022)Background: To examine post-operative pain (PP) after conventional irrigation and sonic activation methods, with and without laser disinfection in mandibular molars. Methods: Eighty patients with symptomatic apical ... -
Efect of prosthetic restorations and root canal fllings on periapical health in a selected patient group
(British Dental Association, 23.07.2021)Aims To examine the efect of the quality of root canal fllings and prosthetic restorations on the frequency of apical periodontitis (AP). Methodology A total of 200 radiographs of 1,098 teeth with indirect restorations ... -
Efective and quick discharge of residual fragments after minimal invasive stone procedures with “EPVL” modality: a new and promising approach
(Springer Nature, 01.07.2020)Residual stone fragments and/or gravel following extracorporeal shock wave lithotripsy (SWL) or retrograde intrarenal surgery (RIRS) constitute a real challenge to the endourologists in clinical practice due to the high ... -
Efects of diferent pulp‑capping materials on cell death signaling pathways of lipoteichoic acid‑stimulated human dental pulp stem cells
(Springer, 2021)Abstract Purpose This study aimed to evaluate the response of dental pulp stem cells (DPSCs) cultured with and without lipoteichoic acid (LTA) to diferent pulp-capping materials. Methods: The cells were cultured and seeded ... -
The efects of instructional environments and cognitive abilities on abstraction performance
(Biruni Üniversitesi, 2022)Abstraction is one of the building blocks in computer science (CS) and is described as omitting details and focusing on the necessary information. One of the approaches in teaching CS is puzzle based learning (PBL) approach ... -
The efects of serum levels, and alterations in the genes of binding protein and receptor of vitamin D on gastric cancer
(Springer Nature, 2019)Due to many biological cell functions of vitamin D including regulation of cell survival, proliferation and differentiation, the metabolism of itself gains importance in the development of several types of cancer. This ... -
The effect of 3 positions given to preterm infants during heelstick procedure on pain and durations of crying and procedure
(Lippincott, Williams & Wilkins, 16.06.2021)The purpose of this randomized controlled study was to determine the effect of 3 positions given to preterm infant during heelstick procedure on the pain and durations of crying and procedure. The sample of the study ... -
Effect of a 980-nm diode laser on post-operative pain after endodontic treatment in teeth with apical periodontitis: A randomized clinical trial
(Springer Nature, 2021)Background: This study aimed to assess the efect of a 980-nm diode laser following chemomechanical root canal preparation on the severity of post-operative pain (PP) after root canal treatment (RCT). Methods: This study ... -
The effect of a cooperative argumentation model on listening and inquiry skills and argument level
(Biruni Üniversitesi, 2021)The aim of this study was to determine the effect of a cooperative argumentation model on the listening and inquiry skills and argument level of pre-service science teachers (PSTs). A mixed method was used. The sample ... -
The effect of a counseling and training program on the treatment of women with overactive bladder
(Routledge, 07.04.2021)Anticholinergic drugs and behavioral interventions are effective methods for the treatment of OAB and UUI. This randomized controlled, prospective, and quasi-experimental study determined the effect of healthy lifestyle ...
