Browsing by Author "Şahin, Pınar"
Now showing items 1-4 of 4
-
Inhibition of mTOR pathway decreases the expression of pre-meiotic and meiotic markers throughout postnatal development and in adult testes in mice
Şahin, Pınar; Güngör-Ordueri, Nazlı Ece; Çelik-Özenci, Çiler (Blackwell Verlag, 11.01.2011)Rapamycin (mTOR inhibitor) has been reported to have negative effect on human male gonadal function. Previously, we showed that mTOR signalling molecules are expressed during early spermatogenesis in mice. The objective ... -
Inhibition of poly(ADP-ribose) polymerase may have preventive potential for varicocoele-associated testicular damage in rats
Çelik-Özenci, Çiler; Kuşcu, Nilay; Güngör-Ordueri, Nazlı Ece; Taşatargil, Arda; Şahin, Pınar; Durmuş, Hacer (WILEY, 2017)Varicocele is ordinarily accompanied by testicular damage and male infertility. Several theories have been proposed to explain the detrimental effect of varicocele on testis tissue, including the possible effects of oxidative ... -
Postnatal fare testis gelişiminde kaspaz-bağımlı ve kaspaz-bağımsız apoptozun değerlendirilmesi
Ordueri, Nazlı Ece Güngör; Elgün, Tuğba; Şahin, Pınar; Kuşcu, Nilay; Özenci, Çiler Çelik (Uludağ Üniversitesi, 2018)Hücre ölümü; testis gelişimi sırasında “kaspaz-bağımlı” ya da mitokondriden salınan Apoptoz indükleyici factor (AIF) gibi çeşitli proapoptotik faktörler aracılığıyla “kaspaz-bağımsız” olmak üzere iki şekilde düzenlenmektedir. ... -
Prediction of the extent of germ cell loss utilising a noninvasive spectroscopy method in rat testicular damage model
Çelik Özenci, Çiler; Sırcan-Küçüksayan, Aslınur; Şahin, Pınar; Güngör-Ordueri, Nazlı Ece; Canpolat, Murat (Blackwell Publishing, 06.2021)The aim of this study is to investigate the efficiency of elastic light single-scattering spectroscopy system, a noninvasive method, to acquire spectra during testicular biopsy from normal and damaged seminiferous tubules ...
