Browsing by Author "Demirkol, Şeyda"
Now showing items 1-5 of 5
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The efects of serum levels, and alterations in the genes of binding protein and receptor of vitamin D on gastric cancer
Durak, Şermin; Gheybi, Arezoo; Demirkol, Şeyda; Arıkan, Soykan; Zeybek, Z.Ümit; Akyüz, Filiz; Yaylım, İlhan; Küçükhüseyin, Özlem (Springer Nature, 2019)Due to many biological cell functions of vitamin D including regulation of cell survival, proliferation and differentiation, the metabolism of itself gains importance in the development of several types of cancer. This ... -
The importance of sPD-1, sOX40L and sGITR in terms of clinicopathology and histopathology in gastric cancer
Horozoğlu, Cem; Sönmez, Dilara; Küçükhüseyin, Özlem; Demirkol, Şeyda; Hakan, Mehmet Tolgahan; Arıkan, Soykan; Yaylım, İlhan (De Gruyter, 2021)Abstract: Objectives: Immunoregulatory GITR, OX40L and PD-1 molecules play an active role in the regulation of tumor microenvironment and have been shown in many cancer types. However, there are limited studies of these ... -
Is there any relationship between LGALS3 gene variations and histopathological criteria in laryngeal squamous cell carcinoma (LSCC)?
Horozoğlu, Cem; Demirkol, Şeyda; Verim, Ayşegül; Sönmez, Dilara; Sürmen, Saime; Küçükhüseyin, Özlem; Zeybek, Ümit; Yaylım, İlhan (De Gruyter, 30.12.2021)Objectives: Genetic variations of LGALS3 (Galectin-3) were found to be associated with treatment resistance, mortality, recurrence, high tumor volume and multiple tumor involvement in solid organ cancers. The modulators ... -
Potential role of immune cell genetic variants associated with tumor microenvironment response in laryngeal squamous cell carcinoma (LSCC) in terms of clinicopathological features
Horozoğlu, Cem; Sönmez, Dilara; Demirkol, Şeyda; Hakan, Mehmet Tolgahan; Kaleler, İslim; Hepokur, Ceylan; Verim, Ayşegül; Yaylım, İlhan (Elsevier GmbH, 12.2021)Immunomodulatory signals regulate the self-tolerance, activation, priming and survival processes of T cells. Programmed cell death protein 1 (PD1), Programmed death-ligand 1 (PD-L1) inhibitory signals and CD27, CD28 ... -
The role of galectin-3 and its genetic variants in tumor risk and survival of patients with surgically resected early-stage non-small cell lung cancer
Terzioğlu-Uşak, Şule; Horozoğlu, Cem; Demirkol, Şeyda; Turna, Akif; Yaylım, İlhan (Türk Göğüs Kalp Damar Cerrahisi Dergisi, 2021)Background: The aim of this study was to investigate the possible relationship between galectin-3 gene variants, serum level, gene expression level, and the risks and survivals of resectable non-small cell lung cancer ...
