Browsing by Author "Ittmann, Michael"
Now showing items 1-8 of 8
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Differential expression of stem cell markers and ABCG2 in recurrent prostate cancer
Güzel, Esra; Karataş, Ömer Faruk; Düz, Mehmet B.; Solak, Mustafa; Ittmann, Michael; Özen, Mustafa (Wiley-Blackwell, 2014)Background. Prostate cancer (PCa) is the second most common tumor type related to mortality in males in the developed countries. Studies have demonstrated that therapeutic tools mostly ineffective to give positive outcome ... -
Identification of microRNAs differentially expressed in prostatic secretions of patients with prostate cancer
Güzel, Esra; Karataş, Ömer Faruk; Semerciöz, Atilla; Ekici, Sinan; Aykan, Serdar; Yentur, Serhat; Creighton, Chad J.; Ittmann, Michael; Özen, Mustafa (Wiley-Blackwell, 2015)Prostate cancer (PCa) is one of the leading causes of cancer deaths in men. Since there are limited treatment options available for the advanced tumors, there is an urgent need for novel diagnostic tools for PCa. Prostate ... -
Kallikrein gene family as biomarkers for recurrent prostate cancer
Böyüközer, Fatma Büşra; Tanoğlu, Esra Güzel; Özen, Mustafa; Ittmann, Michael; Aslan, Elif Sibel (University of Zagreb, 01.2020)Aim To assess kallikrein (KLK) expression in recurrent and non-recurrent prostate tumors and adjacent healthy prostate tissues. Methods The expression levels of 15 KLK genes in 34 recurrent and 36 non-recurrent prostate ... -
miR-1 and miR-133b are differentially expressed in patients with recurrent prostate cancer
Karataş, Ömer Faruk; Güzel, Esra; Süer, İlknur; Ekici, Işın D.; Çaşkurlu, Turhan; Creighton, Chad J.; Ittmann, Michael; Özen, Mustafa (Public Library Science, 2014)Prostate cancer (PCa) is currently the most frequently diagnosed malignancy in the western countries. It is more prevalent in older men with 75% of the incident cases above 65 years old. After radical prostatectomy, ... -
Overexpression of miR-145-5p inhibits proliferation of prostate cancer cells and reduces SOX2 expression
Özen, Mustafa; Karataş, Ömer Faruk; Güllüoğlu, Şükrü; Bayrak, Ömer Faruk; Sevli, Serhat; Güzel, Esra; Ekici, Işın D.; Çaşkurlu, Turhan; Solak, Mustafa; Creighton, Chad J.; Ittmann, Michael (Taylor & Francis Inc, 2015)We aimed to perform functional analysis of miR-145-5p in prostate cancer (PCa) cells and to identify targets of miR-145-5p for understanding its role in PCa pathogenesis. PC3, DU145, LNCaP PCa, and PNT1a nontumorigenic ... -
The role of ATP-binding cassette transporter genes in the progression of prostate cancer
Karataş, Ömer Faruk; Güzel, Esra; Düz, Mehmet B.; Ittmann, Michael; Özen, Mustafa (WILEY, 2016)Background Prostate cancer (PCa) is the most commonly diagnosed neoplasm and the second leading cause of cancer-related death among men in developed countries. There is no clear evidence showing the success of current ... -
Role of miR-145 in human laryngeal squamous cell carcinoma
Karataş, Ömer Faruk; Yücetürk, Betül; Suer, İlknur; Yılmaz, Mehmet; Cansız, Harun; Solak, Mustafa; Ittmann, Michael; Özen, Mustafa (Wiley-Blackwell, 2016)BackgroundLaryngeal squamous cell carcinoma (SCC), being an aggressive malignancy, is one of the most commonly diagnosed malignant types of head and neck SCC worldwide. Incidences of laryngeal SCC have been reported to ... -
The role of miR-145 in stem cell characteristics of human laryngeal squamous cell carcinoma Hep-2 cells
Karataş, Ömer Faruk; Suer, İlknur; Yücetürk, Betül; Yılmaz, Mehmet; Hajiyev, Yusif; Creighton, Chad J.; Ittmann, Michael; Özen, Mustafa (Sage Publications Ltd., 2016)The cancer stem-like cells (CSLCs) are tumorigenic cells promoting initiation, progression, and spread of the tumor. Accumulating evidences suggested the presence of CSLCs in distinct tumors including laryngeal squamous ...
