Browsing by Author "Karataş, Ömer Faruk"
Now showing items 1-18 of 18
-
Alpha-B-crystallin expression in human laryngeal squamous cell carcinoma tissues
Yılmaz, Mehmet; Karataş, Ömer Faruk; Yücetürk, Betül; Dağ, Hüseyin; Yener, Murat; Özen, Mustafa (Wiley, 2015)BackgroundLaryngeal squamous cell carcinoma (SCC), being an aggressive malignancy, is one of the most commonly diagnosed malignant types of head and neck SCC worldwide. The recent studies suggested that B-crystallin might ... -
The altered promoter methylation of oxytocin receptor gene in autism
Yüksel, Mine Elagöz; Yücetürk, Betül; Karataş, Ömer Faruk; Özen, Mustafa; Doğangün, Burak (Taylor & Francis Ltd, 2016)Autism spectrum disorder (ASD) is one of the lifelong existing disorders. Abnormal methylation status of gene promoters of oxytonergic system has been implicated as among the etiologic factors of ASDs. We, therefore, ... -
Circulating miR-21 and eNOS in subclinical atherosclerosis in patients with hypertension
Cengiz, Mahir; Yavuzer, Serap; Avcı, Burçak Kılıçkıran; Yürüyen, Mehmet; Yavuzer, Hakan; Dikici, Süleyman Atilla; Karataş, Ömer Faruk; Özen, Mustafa; Uzun, Hafize; Öngen, Zeki (Taylor & Francis Inc., 2015)Objectives: The aim of this study is to evaluate the relationship of miR-21, nitric oxide (NOx) and endothelial nitric oxide synthase (eNOS) with subclinical atherosclerosis in carotid arteries by measuring carotid intima ... -
Designing a gold nanoparticle-based nanocarrier for microRNA transfection into the prostate and breast cancer cells
Ekin, Aslı; Karataş, Ömer Faruk; Culha, Mustafa; Özen, Mustafa (Wiley-Blackwell, 2014)BackgroundCancer is one of the most common causes of human deaths worldwide. Nanotechnology has the potential to facilitate the detection, diagnosis, and treatment of cancer cases. Successful delivery of nucleic acids into ... -
Differential expression of hypertension-associated microRNAs in the plasma of patients with white coat hypertension
Cengiz, Mahir; Karataş, Ömer Faruk; Koparır, Erkan; Yavuzer, Serap; Ali, Chayar; Yavuzer, Hakan; Kırat, Emre; Karter, Yesari; Özen, Mustafa (Wolters Kluwer Health, 2015)White coat hypertension (WCH) is a high cardiovascular risk condition, and a fundamental understanding of the cause and pathophysiology of the disorder is still lacking. Recent studies demonstrated that microRNAs (miRNAs) ... -
Differential expression of LOXL4 in normal and tumour tissue samples of laryngeal squamous cell carcinoma
Yılmaz, Mustafa; Suer, İlknur; Karataş, Ömer Faruk; Cansız, Harun; Özen, Mustafa (Wiley-Blackwell, 2016)Objective: Head and neck cancer is the sixth most common cancer in worldwide with an increasing incidence rate in recent years. LOXL4 is expressed in several tissues, and its expression has been shown to display a significant ... -
Differential expression of stem cell markers and ABCG2 in recurrent prostate cancer
Güzel, Esra; Karataş, Ömer Faruk; Düz, Mehmet Buğrahan; Solak, Mustafa; Ittmann, Michael; Özen, Mustafa (Wiley-Blackwell, 2014)Background. Prostate cancer (PCa) is the second most common tumor type related to mortality in males in the developed countries. Studies have demonstrated that therapeutic tools mostly ineffective to give positive outcome ... -
Identification of microRNAs differentially expressed in prostatic secretions of patients with prostate cancer
Güzel, Esra; Karataş, Ömer Faruk; Semerciöz, Atilla; Ekici, Sinan; Aykan, Serdar; Yentur, Serhat; Creighton, Chad J.; Ittmann, Michael; Özen, Mustafa (Wiley-Blackwell, 2015)Prostate cancer (PCa) is one of the leading causes of cancer deaths in men. Since there are limited treatment options available for the advanced tumors, there is an urgent need for novel diagnostic tools for PCa. Prostate ... -
Identification of miR-139-5p as a saliva biomarker for tongue squamous cell carcinoma: A pilot study
Düz, Mehmet Buğrahan; Karataş, Ömer Faruk; Güzel, Esra; Turgut, Nesrettin Fatih; Yılmaz, Mehmet; Creighton, Chad J.; Özen, Mustafa (Springer, 2016)Of all human oral carcinomas, 41 % are localized to the tongue. Despite considerable improvements in both diagnosis and treatment, tongue squamous cell carcinoma (TSCC) has remained one of the most lethal types of cancer. ... -
Investigation of doxorubicin combined with ciprofoxacin‑induced cardiotoxicity: From molecular mechanism to fundamental heart function
Shahzadi, Andleeb; Eyileten, Ceren; Postula, Marek; Güzel Tanoğlu, Esra; Karataş, Ömer Faruk; Başçı, Ali Boray; Süzer, Öner; Yazıcı, Zeliha (Springer, 2022)This study was designed to investigate the impacts of Doxo alone and in combination with Cipro on the hepatic and cardiac CYP1A2, CYP2J3, and CYP3A1 mRNA levels. We also aimed to analyze the cardiac function by perfusing ... -
miR-1 and miR-133b are differentially expressed in patients with recurrent prostate cancer
Karataş, Ömer Faruk; Güzel, Esra; Süer, İlknur; Ekici, Işın D.; Çaşkurlu, Turhan; Creighton, Chad J.; Ittmann, Michael; Özen, Mustafa (Public Library Science, 2014)Prostate cancer (PCa) is currently the most frequently diagnosed malignancy in the western countries. It is more prevalent in older men with 75% of the incident cases above 65 years old. After radical prostatectomy, ... -
MiR-221 as a pre- and postoperative plasma biomarker for larynx cancer patients
Yılmaz, Seda Salman; Güzel, Esra; Karataş, Ömer Faruk; Yılmaz, Mehmet; Creighton, Chad J.; Özen, Mustafa (Wiley, 2015)Larynx cancer (LCa), known to be the most commontumor of the head and neck region, accounts for about1% to 2.5% of all human neoplasms, and approximately95% to 98% of LCa is originated from squamous cell car-cinoma.1–3The ... -
Novel POC1A mutation in primordial dwarfism reveals new insights for centriole biogenesis
Koparır, Asuman; Karataş, Ömer Faruk; Yücetürk, Betül; Yüksel, Bayram; Bayrak, Ali O.; Gerdan, Ömer Faruk; Sağıroğlu, Mahmut Şamil; Gezdirici, Alper; Kırımtay, Koray; Selçuk, Ece; Karabay, Arzu; Creighton, Chad J.; Yüksel, Adnan; Özen, Mustafa (Oxford Univ Press, 2015)POC1A encodes a WD repeat protein localizing to centrioles and spindle poles and is associated with short stature, onychodysplasia, facial dysmorphismand hypotrichosis (SOFT) syndrome. These main features are related to ... -
Overexpression of miR-145-5p inhibits proliferation of prostate cancer cells and reduces SOX2 expression
Özen, Mustafa; Karataş, Ömer Faruk; Güllüoğlu, Şükrü; Bayrak, Ömer Faruk; Sevli, Serhat; Güzel, Esra; Ekici, Işın D.; Çaşkurlu, Turhan; Solak, Mustafa; Creighton, Chad J.; Ittmann, Michael (Taylor & Francis Inc, 2015)We aimed to perform functional analysis of miR-145-5p in prostate cancer (PCa) cells and to identify targets of miR-145-5p for understanding its role in PCa pathogenesis. PC3, DU145, LNCaP PCa, and PNT1a nontumorigenic ... -
The role of ATP-binding cassette transporter genes in the progression of prostate cancer
Karataş, Ömer Faruk; Güzel, Esra; Düz, Mehmet Buğrahan; Ittmann, Michael; Özen, Mustafa (WILEY, 2016)Background Prostate cancer (PCa) is the most commonly diagnosed neoplasm and the second leading cause of cancer-related death among men in developed countries. There is no clear evidence showing the success of current ... -
Role of miR-145 in human laryngeal squamous cell carcinoma
Karataş, Ömer Faruk; Yücetürk, Betül; Suer, İlknur; Yılmaz, Mehmet; Cansız, Harun; Solak, Mustafa; Ittmann, Michael; Özen, Mustafa (Wiley-Blackwell, 2016)BackgroundLaryngeal squamous cell carcinoma (SCC), being an aggressive malignancy, is one of the most commonly diagnosed malignant types of head and neck SCC worldwide. Incidences of laryngeal SCC have been reported to ... -
The role of miR-145 in stem cell characteristics of human laryngeal squamous cell carcinoma Hep-2 cells
Karataş, Ömer Faruk; Suer, İlknur; Yücetürk, Betül; Yılmaz, Mehmet; Hajiyev, Yusif; Creighton, Chad J.; Ittmann, Michael; Özen, Mustafa (Sage Publications Ltd., 2016)The cancer stem-like cells (CSLCs) are tumorigenic cells promoting initiation, progression, and spread of the tumor. Accumulating evidences suggested the presence of CSLCs in distinct tumors including laryngeal squamous ... -
Whole-exome sequencing revealed two novel mutations in Usher syndrome
Koparır, Asuman; Karataş, Ömer Faruk; Atayoğlu, Ali Timuçin; Yüksel, Bayram; Sağıroğlu, Mahmut Şamil; Seven, Mehmet; Ulucan, Hakan; Yüksel, Adnan; Özen, Mustafa (Elsevier Science Bv., 2015)Usher syndrome is a clinically and genetically heterogeneous autosomal recessive inherited disorder accompanied by hearing loss and retinitis pigmentosa (RP). Since the associated genes are various and quite large, we ...
