Browsing by Author "Sakagami, Hiroshi"
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Synthesis, biological evaluation and in silico modelling studies of 1,3,5- trisubstituted pyrazoles carrying benzenesulfonamide as potential anticancer agents and selective cancer-associated hCA IX isoenzyme inhibitors
Yamalı, Cem; Gül, Halise İnci; Ece, Abdulilah; Bua, Silvia; Angeli, Andrea; Sakagami, Hiroshi; Şahin, Ertan; Supuran, Claudiu T. (Elsevier B.V., 2019)Inhibition of carbonic anhydrases (CAs, EC 4.2.1.1) has clinical importance for the treatment of several diseases. They participate in crucial regulatory mechanisms for balancing intracellular and extracellular pH of the ...