Browsing by Author "Vedithi, Sundeep Chaitanya"
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Exploring the structural basis of conformational heterogeneity and autoinhibition of human cGMP-specific protein kinase Ia through computational modelling and molecular dynamics simulations
Maryam, Arooma; Khalid, Rana Rehan; Vedithi, Sundeep Chaitanya; Ece, Abdulilah; Çınaroğlu, Süleyman Selim; Siddiqi, Abdul Rauf; Blundell, Tom L. (Elsevier, 2020)Protein kinase Ia (PKGIa) is a pivotal cyclic guanosine monophosphate (cGMP) signalling protein. Major steps related to the structural plasticity of PKGIa have been inferred but the structural aspects of the auto-inhibition ...
