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Overexpression of miR-145-5p inhibits proliferation of prostate cancer cells and reduces SOX2 expression
(Taylor & Francis Inc, 2015)
We aimed to perform functional analysis of miR-145-5p in prostate cancer (PCa) cells and to identify targets of miR-145-5p for understanding its role in PCa pathogenesis. PC3, DU145, LNCaP PCa, and PNT1a nontumorigenic ...
Differential expression of stem cell markers and ABCG2 in recurrent prostate cancer
(Wiley-Blackwell, 2014)
Background. Prostate cancer (PCa) is the second most common tumor type related to mortality in males in the developed countries. Studies have demonstrated that therapeutic tools mostly ineffective to give positive outcome ...
miR-1 and miR-133b are differentially expressed in patients with recurrent prostate cancer
(Public Library Science, 2014)
Prostate cancer (PCa) is currently the most frequently diagnosed malignancy in the western countries. It is more prevalent in older men with 75% of the incident cases above 65 years old. After radical prostatectomy, ...
Poikiloderma with neutropenia: genotype-ethnic origin correlation, expanding phenotype and literature review
(Wiley-Blackwell, 2014)
Poikiloderma with neutropenia (PN), is a rare genodermatosis associated with patognomic features of poikiloderma and permanent neutropenia. Three common recurrent mutations of related gene, USB1, were considered to be ...
Designing a gold nanoparticle-based nanocarrier for microRNA transfection into the prostate and breast cancer cells
(Wiley-Blackwell, 2014)
BackgroundCancer is one of the most common causes of human deaths worldwide. Nanotechnology has the potential to facilitate the detection, diagnosis, and treatment of cancer cases. Successful delivery of nucleic acids into ...
Alpha-B-crystallin expression in human laryngeal squamous cell carcinoma tissues
(Wiley, 2015)
BackgroundLaryngeal squamous cell carcinoma (SCC), being an aggressive malignancy, is one of the most commonly diagnosed malignant types of head and neck SCC worldwide. The recent studies suggested that B-crystallin might ...
The altered promoter methylation of oxytocin receptor gene in autism
(Taylor & Francis Ltd, 2016)
Autism spectrum disorder (ASD) is one of the lifelong existing disorders. Abnormal methylation status of gene promoters of oxytonergic system has been implicated as among the etiologic factors of ASDs. We, therefore, ...
Prediction of splice site using adaBoost with a new sequence encoding approach
(IEEE, 2016)
The Biological sequence data are increasing rapidly, so there is a vital need of effective method for gene detection. Predicting of splice site is an important part of gene finding. Therefore, attempts to improve the ...
MiR-221 as a pre- and postoperative plasma biomarker for larynx cancer patients
(Wiley, 2015)
Larynx cancer (LCa), known to be the most commontumor of the head and neck region, accounts for about1% to 2.5% of all human neoplasms, and approximately95% to 98% of LCa is originated from squamous cell car-cinoma.1–3The ...
Differential expression of hypertension-associated microRNAs in the plasma of patients with white coat hypertension
(Wolters Kluwer Health, 2015)
White coat hypertension (WCH) is a high cardiovascular risk condition, and a fundamental understanding of the cause and pathophysiology of the disorder is still lacking. Recent studies demonstrated that microRNAs (miRNAs) ...
