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Impact of personality traits, anxiety, depression and hopelessness levels on quality of life in the patients with breast cancer
(Türkiye Meme Hastalıkları Dernekleri Federasyonu, 2018)
Objective: The aim of this study was to investigate the impacts of personality traits, anxiety, depression and hopelessness levels on quality of life in the patients with breast cancer. Materials and methods: The study was ...
The effects of 1,3,5-trisubstituted indole derivatives on cell growth, apoptosis and MMP-2/9 mRNA expression of MCF-7 human breast cancer cells
(Bentham Science Publ Ltd, 2017)
Background: Matrix metalloproteinases are known as extracellular matrix degrading enzymes and have important role on tumor progression. Objective: This study reports the effects of 1,3,5-trisubstituted indole derivatives ...
Receptor discordance rate and its effects on survival in primary and recurrent breast cancer patients
(Journal of Buon, 2016)
Purpose: The receptor status of breast cancer plays a critical role in clinical practice. During the metastatic process, a change in the biological characteristics of the tumor can be seen. This study aimed to investigate ...
Synchronous and metachronous bilateral breast cancer: a long-term experience
(Imprimatur Publications, 2018)
Purpose: The objective of this study was to assess the demographic, pathologic and survival characteristics of patients who were diagnosed as having bilateral breast cancer. Methods: A review was conducted of the records ...
Usefulness of imaging findings in predicting tumor-infiltrating lymphocytes in patients with breast cancer
(Springer Nature, 2020)
Objectives Tumor-infiltrating lymphocytes (TILs) have been determined as a new prognostic indicator of immunotherapy response in breast cancer (BC). The aim of this study is to investigate the effectiveness of imaging ...
Tamoxifen / raloxifene loaded liposomes for oral treatment of breast cancer
(Editions de Sante, 26.02.2020)
Breast cancer is the most common type of cancer and it is the second common cause of cancer-related deaths in women. Hormonal therapy is a quite well-tolerated treatment, for estrogen receptor (ER) and progesterone ...
Next-generation sequencing identifies brca1 and/or brca2 mutations in women at high hereditary risk for breast cancer with shorter telomere length
(Mary Ann Liebert, 2020)
Telomeres, and telomere length in particular, have broad significance for genome biology and thus are prime research targets for complex diseases such as cancers. In this context, BRCA1 and BRCA2 gene mutations have been ...
Metformin suppresses the proliferation and invasion through NF-kB and MMPs in MCF-7 cell line
(Türk Biyokimya Derneği, 15.01.2019)
Objective: MCF-7 cells, a breast cancer cell line, are used for experiments of estrogen receptor (ER)-positive breast cancer and many sub-clones representing different classes of ER-positive tumors. We aimed to determine ...
Clinical outcome and toxicity from taxanes in breast cancer patients with BRCA1 and BRCA2 pathogenic germline mutations
(Wiley Periodicals, 08.2020)
Germline variations in genes coding for proteins involved in the oxidative stress and DNA repair greatly influence drug response and toxicity. Because BRCA1 and BRCA2 proteins play a role in DNA damage repair, we postulated ...
Pre - treatment and post - treatment anxiety, depression, sleep and sexual function levels in patients with breast cancer
(urkish Federation of Breast Diseases Associations, 17.04.2020)
Objective: In the phase of diagnosis and treatment of breast cancer cases, patients can usually experience sexual dysfunctions, sleep disorders and psychiatric disorders such as anxiety and depression. The main objective ...