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Postnatal fare testis gelişiminde kaspaz-bağımlı ve kaspaz-bağımsız apoptozun değerlendirilmesi
(Uludağ Üniversitesi, 2018)
Hücre ölümü; testis gelişimi sırasında “kaspaz-bağımlı” ya da mitokondriden salınan Apoptoz indükleyici factor (AIF) gibi çeşitli proapoptotik faktörler aracılığıyla “kaspaz-bağımsız” olmak üzere iki şekilde düzenlenmektedir. ...
Ailelerin sarsılmış bebek sendromuna dair bilgi düzeyi
(Hayat Sağlık ve Sosyal Hizmetler Vakfı, 2018)
Amaç: Çalışmamızda ailelerin çeşitli beyin hasarlarına yol açabilen sarsılmış bebek sendromuna dair bilgi düzeylerini ölçmeyi amaçladık. Gereç ve Yöntemler: Çalışma Ocak–Mart 2016 tarihleri arasında %8,6’sı (n=16) baba, ...
Impact of personality traits, anxiety, depression and hopelessness levels on quality of life in the patients with breast cancer
(Türkiye Meme Hastalıkları Dernekleri Federasyonu, 2018)
Objective: The aim of this study was to investigate the impacts of personality traits, anxiety, depression and hopelessness levels on quality of life in the patients with breast cancer. Materials and methods: The study was ...
Ex vivo protective effects of nicotinamide and 3-aminobenzamide on rat synaptosomes treated with A beta(1-42)
(Wiley, 2014)
Alzheimer's disease (AD) is the most common form of dementia and is characterized by the presence of senile plaques and neurofibrillary tangles, along with synaptic loss. The underlying mechanisms of AD are not clarified ...
Overexpression of miR-145-5p inhibits proliferation of prostate cancer cells and reduces SOX2 expression
(Taylor & Francis Inc, 2015)
We aimed to perform functional analysis of miR-145-5p in prostate cancer (PCa) cells and to identify targets of miR-145-5p for understanding its role in PCa pathogenesis. PC3, DU145, LNCaP PCa, and PNT1a nontumorigenic ...
Differential expression of stem cell markers and ABCG2 in recurrent prostate cancer
(Wiley-Blackwell, 2014)
Background. Prostate cancer (PCa) is the second most common tumor type related to mortality in males in the developed countries. Studies have demonstrated that therapeutic tools mostly ineffective to give positive outcome ...
miR-1 and miR-133b are differentially expressed in patients with recurrent prostate cancer
(Public Library Science, 2014)
Prostate cancer (PCa) is currently the most frequently diagnosed malignancy in the western countries. It is more prevalent in older men with 75% of the incident cases above 65 years old. After radical prostatectomy, ...
Comparison of risk factors for cardiovascular disease in hemodialysis and peritoneal dialysis patients
(Hospital Clinicas, Univ Sao Paulo, 2015)
Objectıve: In this study, we aimed to compare the cardiovascular risk factors that might be associated with inflammation, atherosclerosis and metabolic syndrome between hemodialysis and peritoneal dialysis patients. Methods: ...
Poikiloderma with neutropenia: genotype-ethnic origin correlation, expanding phenotype and literature review
(Wiley-Blackwell, 2014)
Poikiloderma with neutropenia (PN), is a rare genodermatosis associated with patognomic features of poikiloderma and permanent neutropenia. Three common recurrent mutations of related gene, USB1, were considered to be ...
Designing a gold nanoparticle-based nanocarrier for microRNA transfection into the prostate and breast cancer cells
(Wiley-Blackwell, 2014)
BackgroundCancer is one of the most common causes of human deaths worldwide. Nanotechnology has the potential to facilitate the detection, diagnosis, and treatment of cancer cases. Successful delivery of nucleic acids into ...