Eczacılık Fakültesi
Sub-communities within this community
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Analitik Kimya Ana Bilim Dalı [10]
Department of Analytical Chemistry -
Biyokimya Anabilim Dalı [20]
Department of Biochemistry -
Eczacılık Yönetimi Bölümü [4]
Department of Pharmacy Management -
Farmakognozi Anabilim Dalı [12]
Department of Pharmacognosy -
Farmakoloji Anabilim Dalı [7]
Department of Pharmacology -
Farmasötik Botanik Anabilim Dalı [2]
Department of Pharmaceutical Botany -
Farmasötik Kimya Anabilim Dalı [58]
Department of Pharmaceutical Chemistry -
Farmasötik Mikrobiyoloji Ana Bilim Dalı [4]
Pharmaceutical Microbiology Department -
Farmasötik Teknoloji Anabilim Dalı [33]
Department of Pharmaceutical Technology -
Farmasötik Toksikoloji Ana Bilim Dalı [16]
Department of Pharmaceutical Toxicology
Recent Submissions
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Nose-to-brain delivery of peptides and proteins
(Springer, 2023)Abstract The fact that BBB is an important obstacle in drug delivery to the brain has revealed the need o try alternative drug administration routes. One of these alternative ways, also called non-invasive administrations, ... -
Penetration of nanosized matter
(American Scientific Publishers, 2011)Penetration of Nanosized Matter -
Penetration of drugs through skin
(Jaypee Brothers Medical Publishers, 2002)Penetration of drugs through skin -
Pharmacophore-based virtual screening: Identification of selective sirtuin 2 inhibitors
(Marmara Üniversitesi, 2023)ABSTRACT: The Class III histone deacetylases protein Sirt2 has been implicated in the pathogenesis of several agerelated diseases such as inflammation, cancer, and type II diabetes and is considered an attractive novel ... -
Novel coumarin-chalcone derivatives: Synthesis, characterization, antioxidant, cyclic voltammetry, molecular modelling and biological evaluation studies as acetylcholinesterase, α-glycosidase, and carbonic anhydrase inhibitors
(SpringerLink, 2023)ABSTRACT In this study, a total of 12 coumarin-chalcone derivatives, 6 of which are original were synthesized. The structures of the newly synthesized compounds were elucidated by 1 H NMR, 13C NMR, IR, and elemental analysis ... -
Identification of selective inhibitors for phosphodiesterase 5A using e-pharmacophore modelling and large-scale virtual screening-based structure guided drug discovery approaches
(Taylor & Francis, 2023)ABSTRACT The inhibition of Phosphodiesterase 5A (PDEA5) has the potential to modulate pulmonary arterialhypertension and cardiovascular diseases. Exploring the cross-reactivity of clinically available PDE5Atherapeutics ... -
Novel beta-lactam substituted benzenesulfonamides: in vitro enzyme inhibition, cytotoxic activity and in silico interactions
(Taylor & Francis, 2023)Abstract Abstract : In this study, a library of twelve beta-lactam-substituted benzenesulfonamides (5a–l) was synthesized using the tail-approach method. The compounds were characterized using IR, 1H NMR, 13C NMR and ... -
Novel fluorescein isothiocyanate (FITC) cored PAMAM dendrimers as drug delivery agent
(Taylor & Francis, 2023)Abstract Fluorescent dyes, or fluorophores, enable researchers to visualize specific biological molecules by fluorescence microscopy. Herein, a novel fluorescent FITC-poly(amidoamine) (FITC-PAMAM) dendrimers have been ... -
The role of chromatin-modifying enzymes and histone modifications in the modulation of p16 gene in fumonisin B-1-induced toxicity in human kidney cells
(SpringerLink, 2023)Abstract Fumonisin B-1 (FB1) poses a risk to animal and human health. Although the effects of FB1 on sphingolipid metabolism are well documented, there are limited studies covering the epigenetic modifications and early ... -
Heteroatom-doped graphene oxide-based conductive ink: synthesis, characterization and investigation of conductivity properties for flexible sensor technology
(Royal Society of Chemistry, 2023)Abstract The desire for real-time and continuous human health monitoring and uninterrupted human-machine interaction has been increasing exponentially day by day. This has opened new windows in the development of wearable ... -
The discovery of potential cyclin A/CDK2 inhibitors: a combination of 3D QSAR pharmacophore modeling, virtual screening, and molecular docking studies
(SpringerLink, 2013)Abstract Cyclin-dependent kinases are a family of enzymes that regulates the cell cycle process. They have been found to be novel targets for potential anti-cancer drugs. In the present study, a 3D pharmacophore model has ... -
Gen Bilgisi Destekli İlaç Tedavisinin Neresindeyiz?
(Biruni Üniversitesi, 2023)Son yıllarda kardiyovasküler hastalık insidans ve prevalansında gözle görülür bir artış yaşanmaktadır¹²³⁴. Dünyada, bulaşıcı olmayan hastalıklara (BOH) bağlı ölümlerin %44’ü (17,9 milyon) kalp ve damar hastalıklarına, ... -
Soğuk Algınlığı ve Grip Tedavisinde Fitoterapi Uygulamaları
(Biruni Üniversitesi, 2023)Soğuk algınlığı, hafif şiddetteki üst solunum yolu hastalıkları için yaygın olarak kullanılan bir terimdir. Burun tıkanıklığı veya burun akıntısı, hapşırma, boğaz ağrısı ve öksürük soğuk algınlığının en bilinen semptomlarıdır. ... -
Sirkadiyen Ritim ile Diyabet İlişkisi
(Biruni Üniversitesi, 2023)Sirkadiyen sistem, vücut fonksiyonları için hayati önem taşıyan yaklaşık 24 saatlik endojen ritimler üretmektedir. Glikoz metabolizması da dahil olmak üzere kardiyovasküler fonksiyonlar, termoregülasyon gibi birçok günlük ... -
Design, synthesis, and evaluation of a new series of hydrazones as small-molecule akt inhibitors for NSCLC therapy
(American Chemical Society, 2023)Abstract In an endeavor to identify small molecules for the managementofnon-small-cell lung carcinoma, 10 new hydrazone derivatives (3a-j) were synthesized. MTT test was conducted to examinetheir cytotoxic activities ... -
A novel approach for ultrasensitive amperometric determination of NADH via graphene based electrode obtained by electrochemical intercalation of tetraalkylammonium ions
(Springer, 2023)Abstract The reduced β-nicotinamide adenine dinucleotide (NADH) is an important coenzyme in many biological systems. In this work, a new electrochemical sensor platform prepared using tetraoctylammonium ions (TOA+) as an ... -
Structural characterization and biological evaluation of uracil-appended benzylic amines as acetylcholinesterase and carbonic anhydrase I and II inhibitors
(Elsevier, 2023)Abstract A series of novel uracil-appended benzylic amines were synthesized through reductive amination with moderate to good yields (30–84% yields). In situ prepared 5-(arylidene)-6-aminouracils with the condensation ... -
Towards a better understanding of commonly used medicinal plants from Turkiye: Detailed phytochemical screening and biological activity studies of two Teucrium L. species with in vitro and in silico approach
(Elsevier, 2023)Abstract Ethnopharmacological relevance: Since ancient times, Teucrium L. species have been among the most commonly used traditional medicinal plants mainly in the Mediterranean region. From tackling gastrointestinal ... -
Electrochemistry test strip as platform for ın situ detection of blood levels of antipsychotic clozapine in finger-pricked sample volume
(MDPI, 2023)Abstract: With the increasing number of patients suffering from Parkinson’s disease, the importance of measuring drug levels in patient body fluids has increased exponentially, particularly for the drug clozapine. There ... -
Computer-aided drug design
(BMC, 2023)Abstract Computer-Aided Drug Design tools are now an indispensable part of drug discovery that have made key contributions to the development of drugs. In this editorial, I briefly provide an overview of CADD emphasizing ...
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