Advanced Search

Show simple item record

dc.contributor.authorİslamoğlu, Mehmet Sami
dc.contributor.authorGülçiçek, Sibel
dc.contributor.authorSeyahi, Nurhan
dc.date.accessioned2022-02-23T06:41:36Z
dc.date.available2022-02-23T06:41:36Z
dc.date.issued01.12.2022en_US
dc.identifier.issn15256049
dc.identifier.urihttps://doi.org/10.1080/0886022X.2022.2035763
dc.identifier.urihttps://hdl.handle.net/20.500.12445/1815
dc.description.abstractIntroduction: Kidney interstitial fibrosis is an important risk factor for the progression of chronic kidney disease. Kidney elastography is a noninvasive imaging modality that might be used to assess tissue fibrosis. In this study, we aimed to investigate the relationship between tissue stiffness detected in kidney elastography and interstitial fibrosis observed in kidney biopsy. Materials and methods: Patients who were hospitalized in a tertiary care university hospital with a kidney biopsy indication were included in this study. In all patients, the transverse and sagittal elastography measurements were made using a sonoelastography device before the biopsy. The total histological score was calculated. Results: Fifty-seven native kidney patients with proteinuria were included in the study. Patients were divided into two groups according to the presence (n ¼ 6) and absence of fibrosis (n ¼ 51) as detected by kidney biopsy. A significant correlation was found between the presence of fibrosis detected by biopsy and elastography outcomes (p ¼ .046, r ¼ .192). A significant correlation was found between the urea and creatinine levels and transverse elastography measurements (p ¼ .036, r ¼ .240). No correlation was observed between the transverse elastography measurements and total histological score consisting of glomerular, vascular, and tubular scores (r ¼ .006, p ¼ .967) Conclusion: The findings of our study suggest a significant relationship between the elastography measurements and interstitial fibrosis. Because of the high negative predictive value (91%), we suggest that elastography should mainly be used as an exclusion test for the presence of fibrosis. We also believe that elastography may be useful to evaluate the fibrosis status in kidney diseases.en_US
dc.language.isoengen_US
dc.publisherTaylor & Francisen_US
dc.relation.isversionofhttps://doi.org/10.1080/0886022X.2022.2035763en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/us/*
dc.subjectElastography Interstitial Fibrosisen_US
dc.subjectKidneyen_US
dc.subjectKidney Biopsyen_US
dc.titleKidney tissue elastography and interstitial fibrosis observed in kidney biopsyen_US
dc.typearticleen_US
dc.relation.journalRenal Failureen_US
dc.contributor.departmentTıp Fakültesien_US
dc.identifier.volume44en_US
dc.identifier.issue1en_US
dc.identifier.startpage1en_US
dc.identifier.endpage7en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record

info:eu-repo/semantics/openAccess
Except where otherwise noted, this item's license is described as info:eu-repo/semantics/openAccess