The effects of substance use disorder on respiratory function parameters and functional capacity in Istanbul
Görek Dilektaşlı, Aslı
Kaya Mutlu, Ebru
Razak Özdinçler, Arzu
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Background: The aim of our study was to investigate the effects of substance use disorder (SUD) on respiratory function parameters, respiratory muscle strength and functional capacity. Methods: A total of 302 individuals, including 183 SUD adults and age-matched 54 tobacco-smokers and 65 non-smokers were included in the current study. Respiratory functions, respiratory muscle strength, and the functional capacity (6-MWT) of the participants were evaluated. This study was supported by the Turkish Thoracic Society (Project no: Y-110/2018). Results: A 86.3% of the SUD adults included in the study were using heroin, 9.2% were cannabis, and 5.5% were spice. The average amount of tobacco smoking was 20.7±15.8 packs/year for the SUD adults, while 10.2±12.6 packs/year for tobacco-smokers. There was a statistically significant difference between SUD adults, smokers and non-smokers in terms of respiratory function test parameters, respiratory muscle strength, and 6-MWT (p<0.05). Tobacco smoking duration was found as a confounding factor for respiratory function test, respiratory muscle strength and 6-MWT parameters (p<0.0001, p<0.0001, and p<0.03, respectively). Conclusions: Pulmonary function test parameters of SUD adults were found to be significantly lower than non-smokers. In addition, both inspiratory and expiratory respiratory muscle strength values of SUD adults were significantly decreased compared to both tobacco smokers and non-smokers. Also, it was found that the functional capacity of SUD adults decreased significantly compared to both tobacco-smokers and non-smokers.
SourceEuropean Respiratory Journal
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