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dc.contributor.authorErdoğan, Ömer
dc.contributor.authorPaşa, Salih
dc.contributor.authorDemirbolat, Gülen Melike
dc.contributor.authorÇevik, Özge
dc.date.accessioned2022-03-04T11:44:16Z
dc.date.available2022-03-04T11:44:16Z
dc.date.issued2021en_US
dc.identifier.issn13000527
dc.identifier.urihttps://doi.org/10.3906/kim-2102-2
dc.identifier.urihttps://hdl.handle.net/20.500.12445/2029
dc.description.abstractThe green method of nanoparticle synthesis, which is an environment and living-friendly method, is an updated subject that has appeared as an alternative to conventional methods such as physical and chemical synthesis. In this presented study, the green synthesis of magnetic iron oxide nanoparticles (IONPs) from iron (III) chloride by using Brassica oleracea var. capitata sub.var. rubra aqueous peel extract has been reported. The prepared IONPs were characterized with fourier-transform infrared spectroscopy (FTIR), ultraviolet-visible spectroscopy (UV-VIS), zeta potential, scanning electron microscopy (SEM), and energy-dispersive X-ray spectroscopy (EDX). The cytotoxic effects of IONPs on MCF-7 breast cancer cell line were studied by MTT assay, and migrative effect of its were carried out by the wound healing assay. It was found that the mean particle size of IONPs was 675 } 25 nm, and the polydispersity index was 0.265 PDI. It was also determined that these nanoparticles had an anti-proliferative impact on the MCF-7 breast cancer cell line depending on the dosage. Characterization results support the successful synthesis of nanoparticles, and the dosedependent cytotoxic effects of nanoparticles on MCF-7 cells also make it a potential chemotherapeutic agent for breast cancer treatment.en_US
dc.language.isoturen_US
dc.publisherTUBITAKen_US
dc.relation.isversionofhttps://doi.org/10.3906/kim-2102-2en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/us/*
dc.subjectGreen Synthesisen_US
dc.subjectIron Oxide Nanoparticlesen_US
dc.subjectRed Cabbageen_US
dc.subjectBrassica Oleracea Var. Capitata Sub.Var. Rubraen_US
dc.subjectBreast Canceren_US
dc.titleGreen biosynthesis, characterization, and cytotoxic effect of magnetic iron nanoparticles using brassica oleracea var capitata sub var rubra (red cabbage) aqueous peel extracten_US
dc.typearticleen_US
dc.relation.journalTurkish Journal of Chemistryen_US
dc.contributor.departmentEczacılık Fakültesien_US
dc.contributor.authorID0000-0002-8327-7077en_US
dc.contributor.authorID0000-0002-4792-8821en_US
dc.contributor.authorID0000-0001-5621-5818en_US
dc.contributor.authorID0000-0001-5621-5818en_US
dc.identifier.volume45en_US
dc.identifier.issue4en_US
dc.identifier.startpage1en_US
dc.identifier.endpage11en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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