Now showing items 1-3 of 3
Synthesis and characterization of novel ssDNA X-aptamers targeting growth hormone releasing hormone (GHRH)
(Public Library of Science, 01.2022)
Background Growth Hormone Releasing Hormone (GHRH), 44 amino acids containing hypothalamic hormone, retains the biological activity by its first 29 amino acids. GHRH (NH2 1-29) peptide antagonists inhibit the growth of ...
Epibrassinolide prevents tau hyperphosphorylation via GSK3β inhibition in vitro and improves caenorhabditis elegans lifespan and motor deficits in combination with roscovitine
Glycogen synthase kinase 3β (GSK3β) is considered an important element of glycogen metabolism; however, it has many other regulatory roles. Changes in the GSK3β signaling mechanism have been associated with various disorders, ...
In vitro investigations of miR 33a expression in estrogen receptor targeting therapies in breast cancer cells
Background: Increased fatty acid synthesis leads to the aggressive phenotype of breast cancer and renders efficiency of therapeutics. Regulatory microRNAs (miRNAs) on lipid biosynthesis pathways as miR-33a have potential ...