• The Therapeutic effect of aerobic, resistance and combined exercise in vascular dementia rat model by improving cognitive function 

  Ökten, Oğuzhan; Koyuncuoğlu, Türkan; Aydil, Serra; Karaşahin, Elif; Koşar, Fatih Emin; Oruç, Furkan; Özturk, Sinem; Şener, Dila; Çakır, Özgür Kasımay (Scandinavian Physiological Society, 02.2022)

  [No abstract avaiable]

• Effects of different exercise models on parkinson's disease model on cognitive function and the underlying mechanism 

  Koyuncuoğlu, Türkan; Erol, Gökçe; Çulpan, Yekta; Gülhan, Rezzan; Yüksel, Meral; Özkan, Naziye; Çakır, Özgür Kasımay (Scandinavian Physiological Society, 02.2022)

  [No abstract avaiable]

• Neuroprotective effect of cinnamaldehyde on secondary brain injury after traumatic brain injury in a rat model 

  Kuru Bektaşoğlu, Pınar; Koyuncuoğlu, Türkan; Demir, Dilan; Sucu, Gizem; Akakın, Dilek; Peker Eyüboğlu, İrem; Yüksel, Meral; Çelikoğlu, Erhan; Yeğen, Berrak Ç.; Gürer, Bora (Elsevier, 09.2021)

  Objective: The aim of this study was to investigate the possible neuroprotective effects of cinnamaldehyde (CA) on secondary brain injury after traumatic brain injury (TBI) in a rat model. Methods: Rats were randomly divided ...

• Nesfatin-1 ameliorates oxidative brain damage and memory impairment in rats induced with a single acute epileptic seizure 

  Arabacı Tamer, Sevil; Koyuncuoğlu, Türkan; Karagöz Köroğlu, Ayça; Akakın, Dilek; Yüksel, Meral; Ç. Yegen, Berrak (Elsevier, 01.04.2022)

  Aims: We aimed to investigate putative neuroprotective effects of nesfatin-1 on oxidative brain injury and memory dysfunction induced by a single epileptic seizure and to compare these effects with those of antiepileptic ...

• Neuroprotective effect of plasminogen activator inhibitor‑1 antagonist in the rat model of mild traumatic brain injury 

  Kuru Bektaşoğlu, Pınar; Koyuncuoğlu, Türkan; Akbulut, Selin; Akakın, Dilek; Peker Eyüboğlu, İrem; Erzik, Can; Yüksel, Meral; Kurtel, Hızır (Springer Nature, 19.01.2022)

  Plasminogen activator inhibitor-1 (PAI-1) antagonists are known for their neuroprotective efects. In this study, it was aimed to investigate the possible protective efects of PAI-1 antagonists in a rat mild traumatic brain ...

• The effect of apelin-13 on gastric ischemia/reperfusion injury: the roles of sensory nerves and vagus nerve 

  Birsen, İlknur; İzgüt Uysal, V Nimet; Soylu, Hakan; Üstünel, İsmail (Canadian Science Publishing, 05.2020)

  Apelin is a peptide that plays a role in physiological processes such as angiogenesis, apoptosis, and proliferation. The aim of this study was to investigate the role of capsaicin-sensitive afferent neurons and vagus in ...

• 4-(3,4-dihydroxybenzoyloxymethyl)phenyl-O-β-D-glucopyranoside effect in liver regeneration 

  Fırat, Tülin; Söyler, Gizem; Töre, Fatma; Şit, Mustafa; Kıyan, Aysu; Özgen, Ufuk; Kükner, Aysel (Plaza Fuensanta, 2019)

  Summary. Following an injury or resection, the mammalian liver has the capacity to regain its former volume and functioning by restoring itself. Studies have demonstrated that antioxidants play a role in hepatic regeneration. ...

• Thymoquinone ınhibits neurogenic ınflammation underlying migraine through modulation of calcitonin gene-related peptide release and stabilization of meningeal mast cells in glyceryltrinitrate-ınduced migraine model in rats 

  Kılınç, Erkan; Töre, Fatma; Dağıstan, Yaşar; Buğdaycı, Güler (Springer Nature Switzerland, 2019)

  Two main contributors of sterile neurogenic inflammation underlying migraine pain, calcitonin gene–related peptide (CGRP), and meningeal mast cells (MMCs) play a key role in the activation of the inflammatory cascade ...

• Remote myocardial injury: the protective role of fluoxetine 

  Yaman, Onur M.; Erman, Hayriye; Güner, İbrahim; Tok, Olgu Enis; Pala, Mukaddes; Eşrefoğlu, Mukaddes; Gelişgen, Remise; Uzun, Hafize; Aksu, Uğur; Yelmen, Nermin; Şahin, Gülderen (Canadian Science Publishing, 2018)

  Aortic cross-clamping-induced ischemia-reperfusion (IR) is an important factor in the development of postoperative acute cardiac injury following abdominal aortic surgery. We investigated the possible anti-oxidant/anti-i ...

• The effects of 17 beta-estradiol on blood brain barrier integrity in the absence of the estrogen receptor alpha; an in-vitro model 

  Kuruca, Serap Erdem; Karadenizli, Sabriye; Akgün-Dar, Kadriye; Kapucu, Aysegül; Kaptan, Zülal; Üzüm, Gülay (Elsevier Gmbh, Urban & Fischer Verlag, 2017)

  The blood-brain barrier (BBB), which saves the brain from toxic substances, is formed by endothelial cells. It is mainly composed of tight junction (TJ) proteins existing between endothelial cells. Estrogen is an important ...

• Erişkin hipokampal nörogenezin öğrenme ve hafıza fonksiyonlarındaki rolü 

  Kaptan, Zülal; Üzüm, Gülay (2016)

  Erişkin hipokampal nörogenez, erişkin beyninde yaşam boyu nöral kök hücrelerden yeni fonksiyonel nöron üretimidir. Erişkin beyninde nöron üretimi iki bölgeye sınırlıdır. Bunlardan biri hipokampus dentat girusundaki (DG) ...

• The comparison of effects of applications of compound 48/80 and mast cell mediator suspension on inflammation in rats: a methodological study for acute inflammatory pain 

  Kılınç, Erkan; Dağıstan, Yasar; Çetinkaya, Ayhan; Töre, Fatma (Marmara Üniversitesi, 2019)

  Objective: Inflammation underlies the pathological basis of most diseases. Substance-P is a key mediator that participates in various inflammatory processes and painful conditions. Mast cells (MCs) have a key role in ...

• Effects of thymoquinone on liver miRNAs and oxidative stress in Ehrlich acid mouse solid tumor model 

  Meral, İsmail; Pala, Mukaddes; Akbaş, Furkan; Üstünova, Savaş; Yıldız, Cengiz; Demirel, Metin H. (Taylor & Francis Inc., 2018)

  We investigated the effects of thymoquinone (TQ) on the expression of liver microRNAs (miRNAs), liver histopathology and oxidative stress in Ehrlich acid solid tumor model induced mice. We used 24 male BALB/c mice divided ...

• Serotonergic mechanisms of trigeminal meningeal nociception: Implications for migraine pain 

  Kılınç, Erkan; Guerrero-Toro, Cindy; Zakharov, Andrey; Vitale, Carmela; Gubert-Olive, Max; Koroleva, Ksenia; Timonina, Arina; Luz, Liliana L.; Shelukhina, Irina; Giniatullina, Raisa; Töre, Fatma; Safronov, Boris V.; Giniatullin, Rashid (Pergamon-Elsevier Science Ltd., 2017)

  Serotonergic mechanisms play a central role in migraine pathology. However, the region-specific effects of serotonin (5-HT) mediated via multiple types of receptors in the nociceptive system are poorly understood. Using ...

• The role of adult hippocampal neurogenesis in learning and memory function 

  Kaptan, Zülal; Üzüm, Gülay (Türk Nöroloji Derneği, 2016)

  Adult hippocampal neurogenesis is the lifelong production of new functional neurons from neural stem cells in the adult brain. Production of neurons in the adult brain is limited to two areas. One of these is the subgranular ...

• Salmon calcitonin ameliorates nitroglycerin-induced migraine pain through inhibition of calcitonin-gene related peptide release from trigeminal neurons and c-fos expression in trigeminal nucleus caudalis in rats 

  Kılınç, Erkan; Dağıstan, Yaşar; Kükner, Aysel; Söyler, Gizem; Töre, Fatma (Wiley, 2017)

• Investigation of the effects of seizures induced with penthylenetrazole on biomolecular structure in peripheral tissues with fourier transform infrared spectroscopy method and comparison with oxidative stress markers 

  Üzüm, Gülay; Kuruca, Serap; Kaptan, Zülal; Kapucu, Ayşegül; Dar, Kadriye Akgün; Yılmaz, Ayberk; Yalçınkaya, Olcay Bölükbaşı; Kartal, Sehban; Kaleler, İslim (Wiley, 2017)

• The comparison of the effects of application of compound 48/80 and autologous mast cell mediator suspension on plasma substance-P levels and dural mast cells in rats: A methodological study for acute inflammatory pain 

  Kılınç, Erkan; Dağıstan, Yaşar; Çetinkaya, Ayhan; Töre, Fatma (Wiley, 2017)

• The neurotrophic effect of thymoquinone in pentilentetrazole-induced epilepsy model 

  Pala, Mukaddes; Açıkgöz, Nilgün Pala; Kaçmaz, Sema Karaca; Acar, Seyma; Meral, Ismail; Akbaş, Fahri (Wiley, 2017)

• Neuroprotective effect of thymoquinone through miR-204-3p in 6-hydroxydopamine-induced parkinson model 

  Pala, Mukaddes; Açıkgöz, Nilgün Pala; Polat, Yalçın; Akbaş, Fahri; Erdim, Meryem Betül; Ünsal, Rumeysa; Meral, İsmail; Mengi, Murat (Wiley, 2018)

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