• Protective effects of L-carnitine and co-enzyme Q10 against axidative stress damage in hypertension 

  Mecit, Tarık; Kamıloğlu, Naide Nabıl; Şahin, Pelin; Erdağ, Dinçer; Merhan, Oğuz (Erciyes Üniversitesi, 2023)

  Abstract : In this study, it was aimed to investigate the effects of L-carnitine and Co-enzyme Q10 administration together with ACE Inhibitor (ACE inh.) on oxidative stress parameters in liver, brain and kidney tissues in ...

• Protective effects of chlorella vulgaris in alcohol Intoxication 

  Mecit, Tarık; Kamiloğlu, Naide Nabil (Acil Tıp Uzmanları Derneği, 2022)

  Abstract Objectives: The aim of the study, to investigate the effect of Chlorella vulgaris on the liver, kidney and heart MAPK (Mitogen-activated protein kinase), lipid peroxidation antioxidant enzyme activity with ethyl ...

• The Effect of Thymoquinone on the Calcitonin Gene-Related Peptide Release and Dural Mast Cell Degranulation Induced by Compound -48/80 

  Kılınç, Erkan; Töre, Fatma (Wiley, 2020)

  [No abstract]

• Antioxidant and neuroprotective effects of dexpanthenol in rats induced with traumatic brain injury 

  Kuru Bektaşoğlu, Pınar; Koyuncuoğlu, Türkan; Özaydın, Dilan; Kandemir, Cansu; Akakın, Dilek; Yüksel, Meral; Gürer, Bora; Çelikoğlu, Erhan; Yeğen, Berrak Ç. (Elsevier, 2023)

  Trauma-induced primary damage is followed by secondary damage, exacerbating traumatic brain injury (TBI). Dexpanthenol has been shown to protect tissues against oxidative damage in various inflammation models. This study ...

• Possible anti-inflammatory, antioxidant, and neuroprotective effects of apigenin in the setting of mild traumatic brain injury: An investigation 

  Kuru Bektaşoğlu, Pınar; Demir, Dilan; Koyuncuoğlu, Türkan; Yüksel, Meral; Peker Eyüboğlu, İrem; Karagöz Köroğlu, Ayça; Akakın, Dilek; Yıldırım, Alper; Çelikoğlu, Erhan; Gürer, Bora (Taylor and Francis, 2022)

  Objective: Apigenin is a plant flavone proven with biological properties such as anti-inflammatory, antioxidant, and antimicrobial effects. This study, it was aimed to examine the possible anti-inflammatory, antioxidant, ...

• The Therapeutic effect of aerobic, resistance and combined exercise in vascular dementia rat model by improving cognitive function 

  Ökten, Oğuzhan; Koyuncuoğlu, Türkan; Aydil, Serra; Karaşahin, Elif; Koşar, Fatih Emin; Oruç, Furkan; Özturk, Sinem; Şener, Dila; Çakır, Özgür Kasımay (Scandinavian Physiological Society, 02.2022)

  [No abstract avaiable]

• Effects of different exercise models on parkinson's disease model on cognitive function and the underlying mechanism 

  Koyuncuoğlu, Türkan; Erol, Gökçe; Çulpan, Yekta; Gülhan, Rezzan; Yüksel, Meral; Özkan, Naziye; Çakır, Özgür Kasımay (Scandinavian Physiological Society, 02.2022)

  [No abstract avaiable]

• Neuroprotective effect of cinnamaldehyde on secondary brain injury after traumatic brain injury in a rat model 

  Kuru Bektaşoğlu, Pınar; Koyuncuoğlu, Türkan; Demir, Dilan; Sucu, Gizem; Akakın, Dilek; Peker Eyüboğlu, İrem; Yüksel, Meral; Çelikoğlu, Erhan; Yeğen, Berrak Ç.; Gürer, Bora (Elsevier, 09.2021)

  Objective: The aim of this study was to investigate the possible neuroprotective effects of cinnamaldehyde (CA) on secondary brain injury after traumatic brain injury (TBI) in a rat model. Methods: Rats were randomly divided ...

• Nesfatin-1 ameliorates oxidative brain damage and memory impairment in rats induced with a single acute epileptic seizure 

  Arabacı Tamer, Sevil; Koyuncuoğlu, Türkan; Karagöz Köroğlu, Ayça; Akakın, Dilek; Yüksel, Meral; Yeğen, Berrak Ç. (Elsevier, 01.04.2022)

  Aims: We aimed to investigate putative neuroprotective effects of nesfatin-1 on oxidative brain injury and memory dysfunction induced by a single epileptic seizure and to compare these effects with those of antiepileptic ...

• Neuroprotective effect of plasminogen activator inhibitor‑1 antagonist in the rat model of mild traumatic brain injury 

  Kuru Bektaşoğlu, Pınar; Koyuncuoğlu, Türkan; Akbulut, Selin; Akakın, Dilek; Peker Eyüboğlu, İrem; Erzik, Can; Yüksel, Meral; Kurtel, Hızır (Springer Nature, 19.01.2022)

  Plasminogen activator inhibitor-1 (PAI-1) antagonists are known for their neuroprotective efects. In this study, it was aimed to investigate the possible protective efects of PAI-1 antagonists in a rat mild traumatic brain ...

• The effect of apelin-13 on gastric ischemia/reperfusion injury: the roles of sensory nerves and vagus nerve 

  Birsen, İlknur; İzgüt Uysal, V Nimet; Soylu, Hakan; Üstünel, İsmail (Canadian Science Publishing, 05.2020)

  Apelin is a peptide that plays a role in physiological processes such as angiogenesis, apoptosis, and proliferation. The aim of this study was to investigate the role of capsaicin-sensitive afferent neurons and vagus in ...

• 4-(3,4-dihydroxybenzoyloxymethyl)phenyl-O-β-D-glucopyranoside effect in liver regeneration 

  Fırat, Tülin; Söyler, Gizem; Töre, Fatma; Şit, Mustafa; Kıyan, Aysu; Özgen, Ufuk; Kükner, Aysel (Plaza Fuensanta, 2019)

  Summary. Following an injury or resection, the mammalian liver has the capacity to regain its former volume and functioning by restoring itself. Studies have demonstrated that antioxidants play a role in hepatic regeneration. ...

• Thymoquinone inhibits neurogenic inflammation underlying migraine through modulation of calcitonin gene-related peptide release and stabilization of meningeal mast cells in glyceryltrinitrate-induced migraine model in rats 

  Kılınç, Erkan; Töre, Fatma; Dağıstan, Yaşar; Buğdaycı, Güler (Springer Nature Switzerland, 2019)

  Two main contributors of sterile neurogenic inflammation underlying migraine pain, calcitonin gene–related peptide (CGRP), and meningeal mast cells (MMCs) play a key role in the activation of the inflammatory cascade ...

• The role of adult hippocampal neurogenesis in learning and memory function 

  Kaptan, Zülal; Üzüm, Gülay (Türk Nöroloji Derneği, 2016)

  Adult hippocampal neurogenesis is the lifelong production of new functional neurons from neural stem cells in the adult brain. Production of neurons in the adult brain is limited to two areas. One of these is the subgranular ...

• Erişkin hipokampal nörogenezin öğrenme ve hafıza fonksiyonlarındaki rolü 

  Kaptan, Zülal; Üzüm, Gülay (2016)

  Erişkin hipokampal nörogenez, erişkin beyninde yaşam boyu nöral kök hücrelerden yeni fonksiyonel nöron üretimidir. Erişkin beyninde nöron üretimi iki bölgeye sınırlıdır. Bunlardan biri hipokampus dentat girusundaki (DG) ...

• The comparison of effects of applications of compound 48/80 and mast cell mediator suspension on inflammation in rats: a methodological study for acute inflammatory pain 

  Kılınç, Erkan; Dağıstan, Yaşar; Çetinkaya, Ayhan; Töre, Fatma (Marmara Üniversitesi, 2019)

  Objective: Inflammation underlies the pathological basis of most diseases. Substance-P is a key mediator that participates in various inflammatory processes and painful conditions. Mast cells (MCs) have a key role in ...

• Mast cell degranulation mediates oompound 48/80-induced meningeal vasodilatation underlying migraine pain 

  Kılınç, Erkan; Dağıstan, Yaşar; Töre, Fatma (Marmara Üniversitesi, 2018)

  Objective: The cranial dura mater contains plenty of mast cells and is principally supplied by the middle meningeal artery which has a key role in the generation of headaches. Neurogenic inflammation caused by perivascular ...

• Salmon calcitonin ameliorates migraine pain through modulation of CGRP release and dural mast cell degranulation in rats 

  Kılınç, Erkan; Dağıstan, Yaşar; Kükner, Aysel; Yılmaz, Bayram; Ağuş, Sami; Söyler, Gizem; Töre, Fatma (WILEY, 2018)

  The exact mechanism of migraine pathophysiology still remains unclear due to the complex nature of migraine pain. Salmon calcitonin (SC) exhibits antinociceptive effects in the treatment of various pain conditions. In this ...

• Extracellular ATP induces activation and degranulation of meningeal mast cells through P2X7 receptor: a possible mechanism for migraine pain 

  Guselnikova, Valeriia; Nurkhametova, Dilyara; Kudryavtsev, Igor; Giniatullina, Raisa; Wojciechowski, Sara; Töre, Fatma; Koistinaho, Jari; Malm, Tarja; Giniatullin, Rashid (WILEY, 2018)

• Remote myocardial injury: The protective role of fluoxetine 

  Yaman, Muhittin Onur; Erman, Hayriye; Güner, İbrahim; Tok, Olgu Enis; Pala, Mukaddes; Eşrefoğlu, Mukaddes; Gelişgen, Remise; Uzun, Hafize; Aksu, Uğur; Yelmen, Nermin; Şahin, Gülderen (Canadian Science Publishing, 2018)

  Aortic cross-clamping-induced ischemia-reperfusion (IR) is an important factor in the development of postoperative acute cardiac injury following abdominal aortic surgery. We investigated the possible anti-oxidant/anti-i ...

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