Browsing Makale Koleksiyonu by Issue Date
Now showing items 1-20 of 27
-
Nesfatin-1 ameliorates oxidative brain damage and memory impairment in rats induced with a single acute epileptic seizure
(Elsevier, 01.04.2022)Aims: We aimed to investigate putative neuroprotective effects of nesfatin-1 on oxidative brain injury and memory dysfunction induced by a single epileptic seizure and to compare these effects with those of antiepileptic ... -
The Therapeutic effect of aerobic, resistance and combined exercise in vascular dementia rat model by improving cognitive function
(Scandinavian Physiological Society, 02.2022)[No abstract avaiable] -
Effects of different exercise models on parkinson's disease model on cognitive function and the underlying mechanism
(Scandinavian Physiological Society, 02.2022)[No abstract avaiable] -
The effect of apelin-13 on gastric ischemia/reperfusion injury: the roles of sensory nerves and vagus nerve
(Canadian Science Publishing, 05.2020)Apelin is a peptide that plays a role in physiological processes such as angiogenesis, apoptosis, and proliferation. The aim of this study was to investigate the role of capsaicin-sensitive afferent neurons and vagus in ... -
Neuroprotective effect of cinnamaldehyde on secondary brain injury after traumatic brain injury in a rat model
(Elsevier, 09.2021)Objective: The aim of this study was to investigate the possible neuroprotective effects of cinnamaldehyde (CA) on secondary brain injury after traumatic brain injury (TBI) in a rat model. Methods: Rats were randomly divided ... -
Neuroprotective effect of plasminogen activator inhibitor‑1 antagonist in the rat model of mild traumatic brain injury
(Springer Nature, 19.01.2022)Plasminogen activator inhibitor-1 (PAI-1) antagonists are known for their neuroprotective efects. In this study, it was aimed to investigate the possible protective efects of PAI-1 antagonists in a rat mild traumatic brain ... -
The role of adult hippocampal neurogenesis in learning and memory function
(Türk Nöroloji Derneği, 2016)Adult hippocampal neurogenesis is the lifelong production of new functional neurons from neural stem cells in the adult brain. Production of neurons in the adult brain is limited to two areas. One of these is the subgranular ... -
Erişkin hipokampal nörogenezin öğrenme ve hafıza fonksiyonlarındaki rolü
(2016)Erişkin hipokampal nörogenez, erişkin beyninde yaşam boyu nöral kök hücrelerden yeni fonksiyonel nöron üretimidir. Erişkin beyninde nöron üretimi iki bölgeye sınırlıdır. Bunlardan biri hipokampus dentat girusundaki (DG) ... -
Trimetazidine increases cell survival and inhibits the activation of inflammatory response in sodium taurocholate-induced acute pancreatitis
(International College of Surgeons, 2017)Objective: To evaluate the therapeutic effects of trimetazidine (TMZ) in an experimental acute pancreatitis (AP) model induced with sodium taurocholate (STC). Summary of Background Data: At present, AP is considered a ... -
Serotonergic mechanisms of trigeminal meningeal nociception: Implications for migraine pain
(Pergamon-Elsevier Science Ltd., 2017)Serotonergic mechanisms play a central role in migraine pathology. However, the region-specific effects of serotonin (5-HT) mediated via multiple types of receptors in the nociceptive system are poorly understood. Using ... -
The effects of 17 beta-estradiol on blood brain barrier integrity in the absence of the estrogen receptor alpha; an in-vitro model
(Elsevier Gmbh, Urban & Fischer Verlag, 2017)The blood-brain barrier (BBB), which saves the brain from toxic substances, is formed by endothelial cells. It is mainly composed of tight junction (TJ) proteins existing between endothelial cells. Estrogen is an important ... -
Mast cell degranulation mediates oompound 48/80-induced meningeal vasodilatation underlying migraine pain
(Marmara Üniversitesi, 2018)Objective: The cranial dura mater contains plenty of mast cells and is principally supplied by the middle meningeal artery which has a key role in the generation of headaches. Neurogenic inflammation caused by perivascular ... -
Salmon calcitonin ameliorates migraine pain through modulation of CGRP release and dural mast cell degranulation in rats
(WILEY, 2018)The exact mechanism of migraine pathophysiology still remains unclear due to the complex nature of migraine pain. Salmon calcitonin (SC) exhibits antinociceptive effects in the treatment of various pain conditions. In this ... -
Remote myocardial injury: The protective role of fluoxetine
(Canadian Science Publishing, 2018)Aortic cross-clamping-induced ischemia-reperfusion (IR) is an important factor in the development of postoperative acute cardiac injury following abdominal aortic surgery. We investigated the possible anti-oxidant/anti-i ... -
Effects of thymoquinone on liver miRNAs and oxidative stress in Ehrlich acid mouse solid tumor model
(Taylor & Francis Inc., 2018)We investigated the effects of thymoquinone (TQ) on the expression of liver microRNAs (miRNAs), liver histopathology and oxidative stress in Ehrlich acid solid tumor model induced mice. We used 24 male BALB/c mice divided ... -
4-(3,4-dihydroxybenzoyloxymethyl)phenyl-O-β-D-glucopyranoside effect in liver regeneration
(Plaza Fuensanta, 2019)Summary. Following an injury or resection, the mammalian liver has the capacity to regain its former volume and functioning by restoring itself. Studies have demonstrated that antioxidants play a role in hepatic regeneration. ...
