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Synthesis, characterization, preliminary SAR and molecular docking study of some novel substituted imidazo [2,1-b] [1,3,4] thiadiazole derivatives as antifungal agents
(Springer Birkhauser, 2017)
The aim of this study was to synthesize imidazo [2,1-b] [1,3,4] thiadiazole derivatives, characterize them with various spectroscopic methods and investigate their antifungal activities. 2- Imino - 1,3,4 - thiadiazole ...
An integrated approach towards the development of novel antifungal agents containing thiadiazole: synthesis and a combined similarity search, homology modelling, molecular dynamics and molecular docking study
BackgroundThis study aims to synthesise and characterise novel compounds containing 2-amino-1,3,4-thiadiazole and their acyl derivatives and to investigate antifungal activities. Similarity search, molecular dynamics and ...
Design, synthesis, SAR and molecular modeling studies of novel imidazo [2,1-b][1,3,4] thiadiazole derivatives as highly potent antimicrobial agents
In this study, a novel series of phenyl substituted imidazo[2,1-b][1,3,4]thiadiazole derivatives were synthesized, characterized and explored for antibacterial activity against Gram-negative Escherichia coli, Gram-positive ...