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Novel β hydroxy ketones synthesis, spectroscopic characterization, molecular docking, and anticancer activity studies
In this study, a series of novel β–hydroxy ketone derivatives 3a-o were designed, synthesized, and evaluated for their anticancer activity. The structure of these compounds were characterized by IR, 1H and 13C NMR, mass ...
New bis and tetrakis 1,2,3 triazole derivatives synthesis, DNA cleavage, molecular docking, antimicrobial, antioxidant activity and acid dissociation constants
In this study, a series of bis– and tetrakis–1,2,3–triazole derivatives were synthesized using copper-catalyzed azide-alkyne cycloaddition (CuAAC) click chemistry in 73–95% yield. The bis– and tetrakis–1,2,3–triazoles ...