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Drug repurposing in the development of anticancer agents
(Bentham Science Publ Ltd, 2019)
Background: Research into repositioning known drugs to treat cancer other than the originally intended disease continues to grow and develop, encouraged in part, by several recent success stories. Many of the studies in ...
Synthesis, biological evaluation and in silico modelling studies of 1,3,5- trisubstituted pyrazoles carrying benzenesulfonamide as potential anticancer agents and selective cancer-associated hCA IX isoenzyme inhibitors
(Elsevier B.V., 2019)
Inhibition of carbonic anhydrases (CAs, EC 4.2.1.1) has clinical importance for the treatment of several diseases. They participate in crucial regulatory mechanisms for balancing intracellular and extracellular pH of the ...
