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Resveratrolün kardiyovasküler hastalıklar üzerine etkileri
(Türkiye Diyetisyenler Derneği, 2021)Öz:Kardiyovasküler hastalıklar; dünyada mortalitenin önde gelen nedenlerinden biridir. Kardiyovasküler hastalıklarınönlenmesi ve uygulanan tedavilerin etkisinin arttırılmasında, doğal nutrasötikleri kullanan alternatif ... -
Surface plasmon resonance identifies high-affinity binding of l-DOPA to siderocalin/lipocalin-2 through Iron – siderophore action: Implications for parkinson’s disease treatment
(American Chemical Society, 12.2021)Abstract: L-3,4-Dihydroxyphenylalanine (L-DOPA), the dopamine precursor, remains the frontline treatment for Parkinson's disease (PD). With the treatment progress, L-DOPA efficacy decreases, necessitating higher and more ... -
Effects of somatostatin, curcumin, and quercetin on the fatty acid profile of breast cancer cell membranes
(International Academy of Cardiovascular Sciences, 24.03.2020)Breast cancer is a worldwide commonly found malignancy in women and effective treatment is regarded as a huge clinical challenge even in the presence of several treatment options. Extensive literature is available demonstrating ... -
Hybrid compounds & oxidative stress induced apoptosis in cancer therapy
(Bentham Science Publishers, 14.05.2020)Abstract: Elevated Reactive Oxygen Species (ROS) generated by the conventional cancer therapies and the endogenous production of ROS have been observed in various types of cancers. In contrast to the harmful effects of ... -
The importance of thiol / disulfide homeostasisand ischemia-modified albumin levels in acute coronary syndrome and their relationship with angiographic scoring systems
(European Journal of Therapeutics, 12.2020)Objective: The objective of this study was to investigate the differences in thiol/disulfide homeostasis- and ischemia-modified albumin (IMA) levels that are known to be associated with oxidative damage in patients with ... -
Lab-in-a-syringe : A novel electrochemical biosensor for on-site and real-time monitoring of dopamine in freely behaving mice
(American Chemical Society, 01.2022)There is a growing demand for real-time analysis and sampling of biofluids on a single low-cost platform in ultralow fluid volumes with robustness. In this study, a microfluidic sensor was developed, manufactured through ... -
Effects of somatostatin and vitamin C on the fatty acid profile of breast cancer cell membranes
(Bentham Science Publishers, 17.07.2019)Abstract: Background: Vitamin C (Vit C) is an important physiological antioxidant with growing applications in cancer. Somatostatin (SST) is a natural peptide with growth inhibitory effect in several mammary cancer models. ... -
Ex vivo protective effects of nicotinamide and 3-aminobenzamide on rat synaptosomes treated with A beta(1-42)
(Wiley, 2014)Alzheimer's disease (AD) is the most common form of dementia and is characterized by the presence of senile plaques and neurofibrillary tangles, along with synaptic loss. The underlying mechanisms of AD are not clarified ... -
STAT-dependent upregulation of 12/15-lipoxygenase contributes to neuronal injury after stroke
(Nature Publishing Group, 2015)Oxidative stress is a major brain injury mechanism after ischemic stroke. 12/15-lipoxygenase (12/15-LOX) is a key mediator of oxidative stress, contributing to neuronal cell death and vascular leakage. Nonetheless, the ... -
Nitric oxide mediated effects of nebivolol in myocardial infarction: the source of nitric oxide
(Verduci Publisher, 2015)Objective: After MI pathological LV remodeling is one of the major causes of death. We previously showed the NO mediated beneficial effects of nebivolol in rat MI model, in this study we aimed to evaluate the NOS related ... -
Endometrial mrna expressions of cytokines in women with in vitro fertilization failure
(Pergamon - Elsevier Science, 2016) -
Superoxide dismutase, catalase and guanase in traumatic brain injury
(2005)Objectives: Reactive oxygen species generated after brain trauma trigger a cascade of events resulting in neuronal death. Despite numerous defenses, the brain is vulnerable to oxidative damage, mainly because of its high ...
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