Browsing by Department "Eczacılık Fakültesi"
Now showing items 1-20 of 133
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2.Computer-aided drug design symposium and workshop abstract book
(Biruni Üniversitesi, 2022)The focus of the symposium is to bring together academia and industry with an interest in the validation of novel biomolecule targets to treat disease with an unmet clinical need and in applying computational technologies ... -
2019-nCoV virüsüne karşı etkili olabilecek moleküllerin ilaç yeniden yapılandırma ve makine öğrenim yaklaşım yöntemleri ile saptanması
(Biruni Üniversitesi, 2022)Abstract Tez kapsamında virüsün hızla yayılmasını ve kendi kendine replikasyonunu önlemek için SARS-CoV-2'nin yeni inhibitörlerinin bulunması ve inhibitör tasarlamak için derin öğrenme yöntemi kullanılarak RdRp inhibitörü ... -
Alterations in cell viability, reactive oxygen species production, and modulation of gene expression involved in mitogen–activated protein kinase/extracellular regulating kinase signaling pathway by glyphosate and its commercial formulation in hepatocellular carcinoma cells
(SAGE Publications, 2023)Glyphosate (N-phosphonomethyl glycine) is a non-selective, organophosphate herbicide widely used in agriculture and forestry. We investigated the possible toxic effects of the glyphosate active compound and its commercial ... -
An alternative strategy to detect bacterial contamination in milk and water: A newly designed electrochemical biosensor
(Springer Nature, 2020)The detection of acyl homoserine lactones (AHLs) can render their use as biomarkers and it may provide a chance to fght against food contamination and bacterial pathogens. For this purpose, in this study, an electrochemical ... -
Ameliorative effects of the sesquiterpenoid valerenic acid on oxidative stress induced in hepg2 cells after exposure to the fungicide benomyl
(Multidisciplinary Digital Publishing Institute, 2021)Abstract: Valerenic acid (VA) is a sesquiterpenoid and a phytoconstituent of the plant valerian used for sleeping disorders and anxiety. The frequency of using herbal components as therapeutic nutritional agents has increased ... -
Anti-aging formulation of rosmarinic acid-loaded ethosomes and liposomes
(Taylor & Francis, 2019)Abstract The study was aimed to evaluate the effectiveness of rosmarinic acid (RA) loaded ethosomes (ETHs) and liposomes (LPs) when subjected to the transdermal application. RA-loaded ETHs and LPs were prepared, optimised, ... -
Antimicrobial evaluation, molecular docking and ADME properties of indole amide derivatives
(Bentham, 2022)Abstract Background: Besides the viral infections, bacterial infections can cause serious and life-threatening complications and drug resistance is an important problem to fight bacterial infections. There-fore, it is ... -
Antioxidant capacity measurement based on κ-carrageenan stabilized and capped silver nanoparticles using green nanotechnology
(Elsevier, 15.10.2021)A novel antioxidant capacity (AC) method was designed exploiting the formation and growth mechanism of green synthesized silver nanoparticles (SNPs) using κ-carrageenan. Carrageenan, a natural polysaccharide derived from ... -
Antiproliferative effects of turkish pomegranate (punica granatum l.) extracts on MCF-7 human breast cancer cell lines with focus on antioxidant potential and bioactive compounds analyzed by LC-MS/MS
(Wiley, 09.2021)In this study, eight different pomegranate (Punica granatum L.) cultivars from Turkey were evaluated for their antioxidant and cytotoxic effects on the MCF-7 breast cancer cell lines and MCF-10A breast fibrocystic epithelial ... -
The application of nanogels as efficient drug delivery platforms for dermal/transdermal delivery
(MDPI, 2023)Abstract: The delivery of active molecules via the skin seems to be an efficient technology, given the various disadvantages of oral drug administration. Skin, which is the largest human organ of the body, has the important ... -
Benomyl induced oxidative stress related DNA damage and apoptosis in H9c2 cardiomyoblast cells
(Elsevier, 09.2021)Benomyl, benzimidazole group pesticide, has been prohibited in Europe and USA since 2003 due to its toxic effects and it has been still determined as food and environmental contaminant. In the present study, the toxic ... -
Bioactive indanes: insight into the bioactivity of indane dimers related to the lead anti-inflammatory molecule PH46A
(Royal Pharmaceutical Society, 16.04.2020)Objectives PH46A (1) demonstrates significant anti-inflammatory activity in phenotypic models but its mechanism and site of action have been elusive. Current study focused on the bioactivity of PH46 (2) and related novel ... -
Biofeedback sensor vs. physiotherapist feedback during core stabilization training in patients with chronic nonspecific low back pain
(Springer, 2023)52 of 405 Biofeedback Sensor vs. Physiotherapist Feedback During Core Stabilization Training in Patients with Chronic Nonspecific Low Back Pain By Yeldan, I (Yeldan, Ipek) [1] ; Canan, GD (Canan, Gulvin Dilan) [2] ; ... -
Branding of prescription and non-prescription drugs
(İstanbul Medipol Üniversitesi adına Sorumlu Prof. Dr. Sabahattin Aydın, 2018)It is worthwhile to note that, while health related products are mostly function driven categories, health in itself is an emotive and personal subject. With this perspective, pharmaceutical companies need to focus on ... -
Can carbon quantum dots (CQDs) or boron compounds be an ultimate solution for COVID-19 therapy?
(Iranian Journal of Pharmaceutical Research, 2021)Severe acute respiratory syndrome (SARS) is an infectious and highly transmissible disease that is affected by SARS coronavirus (SARS-CoV) and for which there are presently no approved treatments. COVID-19 is a new strain ... -
Cellular stress pathways are linked to acetamiprid-induced apoptosis in sh-sy5y neural cells
(MDPI, 09.2021)Simple Summary: Neonicotinoids constitute more than one-quarter of the insecticides on the market. Acetamiprid, a widely used neonicotinoid, has been found to be linked with neurological symptoms and there is an urge to ... -
Changing biotechnology dynamics - a blessing or a curse?
(Elsevier B.V., 2019)Technology and organism… The more artificial one is, the more natural the other. In the first place, we can think of two completely opposite concepts. However, we know that ‘the mixture of artificial intelligence and human’ ... -
Changing biotechnology dynamics - a blessing or a curse?
(Elsevier, 2020)Technology and organism . . . The more artificial one is, the more natural the other. In the first place, we can think of two completely opposite concepts. However, we know that ‘the mixture of artificial intelligence ... -
Clinical trials on combination of repurposed drugs and anticancer therapies
(2020)Abstract This chapter provides the clinical applications of existing several therapeutic agents for the treatment of cancer which is called drug repurposing. The main aim of drug repurposing generally is that trying to ... -
The combined use of carbon nanotubes with synthetic ceramics enhances posterolateral fusion: An experimental study in a rat spinal fusion model
(Springer, 2023)Purpose The aim of the present study was to evaluate the efectiveness of carbon nanotubes (CNTs)/ HA–tricalcium phosphate (TCP) composite in a posterolateral spinal fusion model. Methods At frst, CNTs and CNTs/HA–TCP ...
