Browsing by Author "Güzel, Esra"
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Differential expression of stem cell markers and ABCG2 in recurrent prostate cancer
Güzel, Esra; Karataş, Ömer Faruk; Düz, Mehmet Buğrahan; Solak, Mustafa; Ittmann, Michael; Özen, Mustafa (Wiley-Blackwell, 2014)Background. Prostate cancer (PCa) is the second most common tumor type related to mortality in males in the developed countries. Studies have demonstrated that therapeutic tools mostly ineffective to give positive outcome ... -
Identification of microRNAs differentially expressed in prostatic secretions of patients with prostate cancer
Güzel, Esra; Karataş, Ömer Faruk; Semerciöz, Atilla; Ekici, Sinan; Aykan, Serdar; Yentur, Serhat; Creighton, Chad J.; Ittmann, Michael; Özen, Mustafa (Wiley-Blackwell, 2015)Prostate cancer (PCa) is one of the leading causes of cancer deaths in men. Since there are limited treatment options available for the advanced tumors, there is an urgent need for novel diagnostic tools for PCa. Prostate ... -
Identification of miR-139-5p as a saliva biomarker for tongue squamous cell carcinoma: A pilot study
Düz, Mehmet Buğrahan; Karataş, Ömer Faruk; Güzel, Esra; Turgut, Nesrettin Fatih; Yılmaz, Mehmet; Creighton, Chad J.; Özen, Mustafa (Springer, 2016)Of all human oral carcinomas, 41 % are localized to the tongue. Despite considerable improvements in both diagnosis and treatment, tongue squamous cell carcinoma (TSCC) has remained one of the most lethal types of cancer. ... -
İnfertil hastalardaki tedavi süreçlerinin embriyo parametreleri ve in vitro fertilizasyon (IVF) sonuçları üzerine etkileri
Güzel, Esra (Biruni Üniversitesi Sağlık Bilimleri Enstitüsü, 2017)İn vitro fertilizasyon (IVF) tedavisi, günümüzde infertilite tedavisinde en fazla kullanılan yardımcı üreme tekniklerindendir. Yardımcı üreme teknikleri ile yapılan her embriyo transferi için canlı doğum oranının yaklaşık ... -
MDMA abuse in relation to microrna variation in human brain ventral tegmental area and nucleus accumbens
Demirel, Göksun; Güzel, Esra; Creighton, Chad J.; Öztürk, Yeter Erol; Küçük, Ceyhun; Aslıyüksek, Hızır; Yurdun, Türkan (Shaheed Behesti University of Medical Sciences and Health, 04.2019)3,4-methylenedioxymethamphetamine (MDMA) is one of the most widespread illegal drugs, that have been used particularly by young people in the 15-34 age group. MicroRNAs (miRNAs) are endogenously synthesized, non-coding, ... -
A meta-analysis: identification of common mir-145 target Genes that have similar behavior in different GEO datasets
Pashaei, Elnaz; Güzel, Esra; Özgürses, Mete Emir; Demirel, Göksun; Aydın, Nizamettin; Özen, Mustafa (Public Library Science, 2016)Background MicroRNAs, which are small regulatory RNAs, post-transcriptionally regulate gene expression by binding 3'-UTR of their mRNA targets. Their deregulation has been shown to cause increased proliferation, migration, ... -
miR-1 and miR-133b are differentially expressed in patients with recurrent prostate cancer
Karataş, Ömer Faruk; Güzel, Esra; Süer, İlknur; Ekici, Işın D.; Çaşkurlu, Turhan; Creighton, Chad J.; Ittmann, Michael; Özen, Mustafa (Public Library Science, 2014)Prostate cancer (PCa) is currently the most frequently diagnosed malignancy in the western countries. It is more prevalent in older men with 75% of the incident cases above 65 years old. After radical prostatectomy, ... -
MiR-221 as a pre- and postoperative plasma biomarker for larynx cancer patients
Yılmaz, Seda Salman; Güzel, Esra; Karataş, Ömer Faruk; Yılmaz, Mehmet; Creighton, Chad J.; Özen, Mustafa (Wiley, 2015)Larynx cancer (LCa), known to be the most commontumor of the head and neck region, accounts for about1% to 2.5% of all human neoplasms, and approximately95% to 98% of LCa is originated from squamous cell car-cinoma.1–3The ... -
Overexpression of miR-145-5p inhibits proliferation of prostate cancer cells and reduces SOX2 expression
Özen, Mustafa; Karataş, Ömer Faruk; Güllüoğlu, Şükrü; Bayrak, Ömer Faruk; Sevli, Serhat; Güzel, Esra; Ekici, Işın D.; Çaşkurlu, Turhan; Solak, Mustafa; Creighton, Chad J.; Ittmann, Michael (Taylor & Francis Inc, 2015)We aimed to perform functional analysis of miR-145-5p in prostate cancer (PCa) cells and to identify targets of miR-145-5p for understanding its role in PCa pathogenesis. PC3, DU145, LNCaP PCa, and PNT1a nontumorigenic ... -
The role of ATP-binding cassette transporter genes in the progression of prostate cancer
Karataş, Ömer Faruk; Güzel, Esra; Düz, Mehmet Buğrahan; Ittmann, Michael; Özen, Mustafa (WILEY, 2016)Background Prostate cancer (PCa) is the most commonly diagnosed neoplasm and the second leading cause of cancer-related death among men in developed countries. There is no clear evidence showing the success of current ...
