Now showing items 1-5 of 5
Genes that affect brain structure and function identified by rare variant analyses of mendelian neurologic disease
(Cell Press, 2015)
Development of the human nervous system involves complex interactions among fundamental cellular processes and requires a multitude of genes, many of which remain to be associated with human disease. We applied whole exome ...
Differential expression of stem cell markers and ABCG2 in recurrent prostate cancer
Background. Prostate cancer (PCa) is the second most common tumor type related to mortality in males in the developed countries. Studies have demonstrated that therapeutic tools mostly ineffective to give positive outcome ...
The role of ATP-binding cassette transporter genes in the progression of prostate cancer
Background Prostate cancer (PCa) is the most commonly diagnosed neoplasm and the second leading cause of cancer-related death among men in developed countries. There is no clear evidence showing the success of current ...
Identification of miR-139-5p as a saliva biomarker for tongue squamous cell carcinoma: A pilot study
Of all human oral carcinomas, 41 % are localized to the tongue. Despite considerable improvements in both diagnosis and treatment, tongue squamous cell carcinoma (TSCC) has remained one of the most lethal types of cancer. ...
Revealing the function of a novel splice-site mutation of CHD7 in CHARGE syndrome
(Elsevier Science Bv., 2016)
Most cases of CHARGE syndrome are sporadic and autosomal dominant. CHD7 is a major causative gene of CHARGE syndrome. In this study, we screened CHD7 in two Turkish patients demonstrating symptoms of CHARGE syndrome such ...