Effects of different polyvinylpyrrolidone iodine concentrations on trismus and swelling following third molar surgery

Abstract

Abstract Objective: To compare the clinical efficacy of different povidone iodine concentrationsfor the management of postoperative pain and swelling following mandibular third molarsurgery. Methods: The randomised, prospective, double-blind and controlled study was conducted from October 2016 to January 2018 at the Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Biruni University, Istanbul, Turkey, and comprised individuals aged 18-30 years who underwent surgical removal of pathology-free completely unerrupted mandibular lower third molars. The participants were randomly assigned to four groups: Group I had saline-only controls, Group II was given 0.5% concentration of povidone iodine, Group III had 1% concentration of povidone iodine, and Group IV had 3% concentration of povidone iodine. Facialswelling and trismus were assessed on the 2nd and 7th postoperative days. Data was analysed using SPSS 22. Results:Ofthe 80patients, 34(42.5%)weremales and46 (57.5%)were femaleswithanoverallmeanage of 24.6±3.68 years. Each group had 20 (25%) subjects. All three concentrations of povidone iodine provided significant reduction in postoperative trismus compared to the controls. Trismus was less in Group III and Group IV compared to Group II up to 7 days aftersurgery. Conclusion: Irrigationwith3%povidone iodine concentrationwasfoundtobemore effective inreducingthe level offacial swelling after impacted third molarsurgery. (Clinical Trials.gov Identifier: NCT03894722)