Browsing Biyomedikal Mühendisliği by Subject "Atropisomer"

Advanced Search

Now showing items 1-1 of 1

Novel 1,2,4-triazoles derived from Ibuprofen: synthesis and in vitro evaluation of their mPGES-1 inhibitory and antiproliferative activity

Bülbül, Bahadır; Ding, Kai; Zhan, Chang-Guo; Çiftçi, Gamze; Yelekçi, Kemal; Gürboğa, Merve; Özakpınar, Özlem Bingöl; Aydemir, Esra; Baybağ, Deniz; Şahin, Fikrettin; Kulabaş, Necla; Helvacıoğlu, Sinem; Charehsaz, Mohammad; Tatar, Esra; Özbey, Süheyla; Küçükgüzel, İlkay (Springer Nature, 2022)

Abstract Abstract: Some novel triazole-bearing ketone and oxime derivatives were synthesized from Ibuprofen. In vitro cytotoxic activities of all synthesized molecules against five cancer lines (human breast cancer MCF-7, ...